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Stretching Fibroblasts Remodels Fibronectin and Alters Cancer Cell Migration

9 Feb 2015

Abstract excerpt

Most investigations of cancer-stroma interactions have focused on biochemical signaling effects, with much less attention being paid to biophysical factors. In this study, we investigated the role of mechanical stimuli on human prostatic fibroblasts using a microfluidic platform that was adapted for our experiments and further developed for both repeatable performance among multiple assays and for compatibility...

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PMID: 25660754
DOI: 10.1038/srep08334

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