Article
Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data.
Annals of the rheumatic diseases - 1 Jun 2013
Elliott Katherine S, Chapman Kay, Day-Williams Aaron, Panoutsopoulou Kalliope, Southam Lorraine, Lindgren Cecilia M, Arden Nigel, Aslam Nadim, Birrell Fraser, Carluke Ian, Carr Andrew, Deloukas Panos, Doherty Michael, Loughlin John, McCaskie Andrew, Ollier William E R, Rai Ashok, Ralston Stuart, Reed Mike R, Spector Timothy D, Valdes Ana M, Wallis Gillian A, Wilkinson Mark, Zeggini Eleftheria
Abstract excerpt
OBJECTIVES: Obesity as measured by body mass index (BMI) is one of the major risk factors for osteoarthritis. In addition, genetic overlap has been reported between osteoarthritis and normal adult height variation. We investigated whether this relationship is due to a shared genetic aetiology on...
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