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APOL1 variants and kidney disease. There is no such thing as a free lunch.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Mar 2011

Kronenberg Florian

Abstract excerpt

A recent study by Genovese et al. unraveled the findings of the intensively discussed gene region around MYH9 and its association with non-diabetic chronic kidney disease in African-Americans. First, it is not the genetic variation in MYH9 but in the neighbouring APOL1 that causes the strong association with disease in African-Americans and second, the study showed strong evidence for a positive selection against...

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Source

Identifiers

PMID: 21216884
DOI: 10.1093/ndt/gfq753

Genes

APOL1
MYH9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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