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Article

The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium.

Journal of cardiovascular translational research - 1 Dec 2012

Dobaczewski Marcin, de Haan Judith J, Frangogiannis Nikolaos G

Abstract excerpt

Cardiac fibroblasts are key cellular effectors of cardiac repair; their phenotype and function are modulated by interactions with extracellular matrix proteins. This review manuscript discusses the effects of the extracellular matrix on the inflammatory and reparative properties of fibroblasts in the infarcted myocardium. Early generation of matrix fragments in the infarct induces a pro-inflammatory and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22956156
DOI: 10.1007/s12265-012-9406-3
PMCID: PMC3535072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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