Article
The interstitium in cardiac repair: role of the immune-stromal cell interplay.
Nature reviews. Cardiology - 1 Oct 2018
Forte Elvira, Furtado Milena Bastos, Rosenthal Nadia
Abstract excerpt
Cardiac regeneration, that is, restoration of the original structure and function in a damaged heart, differs from tissue repair, in which collagen deposition and scar formation often lead to functional impairment. In both scenarios, the early-onset inflammatory response is essential to clear damaged cardiac cells and initiate organ repair, but the quality and extent of the immune response vary. Immune cells...
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