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Article

Fibroblasts in the Infarcted, Remodeling, and Failing Heart

1 Jun 2019

Abstract excerpt

Expansion and activation of fibroblasts following cardiac injury is important for repair but may also contribute to fibrosis, remodeling, and dysfunction. The authors discuss the dynamic alterations of fibroblasts in failing and remodeling myocardium. Emerging concepts suggest that fibroblasts are not unidimensional cells that act exclusively by secreting extracellular matrix proteins, thus promoting fibrosis and...

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Identifiers

PMID: 31312768
DOI: 10.1016/j.jacbts.2019.02.006

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