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Article

Role of murine models in psychiatric illness drug discovery: a dimensional view.

Expert opinion on drug discovery - 1 Jul 2013

Hoffman Kurt Leroy

Abstract excerpt

INTRODUCTION: The extensive comorbidity among psychiatric disorders underscores the need for a fundamental change in the way psychopathology is classified. An alternative 'dimensional' system classifies disorders based on relationships with respect to heritability patterns and comorbidity. It is from this 'dimensional view' that mouse modeling of neuropsychiatric disorders is presently discussed. AREAS COVERED:...

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Identifiers

PMID: 23651279
DOI: 10.1517/17460441.2013.797959

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