Article
Muscle length and myonuclear position are independently regulated by distinct Dynein pathways
6 Sept 2012
Abstract excerpt
Various muscle diseases present with aberrant muscle cell morphologies characterized by smaller myofibers with mispositioned nuclei. The mechanisms that normally control these processes, whether they are linked, and their contribution to muscle weakness in disease, are not known. We examined the role of Dynein and Dynein-interacting proteins during Drosophila muscle development and found that several factors,...
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