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Article

Interplay between microtubule interactome, myonuclei mechanotransduction, and positioning in myopathies

3 Jul 2025

Abstract excerpt

Myofibers are the building block of skeletal muscle cells providing its capacity to contract and produce movement. The microtubule (MT) network sustains myofiber formation and its spatial organization is remodel during myofiber formation. This muscle-related MT network with specific partners, actively drive myonuclei localization in myofiber. In pathological conditions, myonuclei and MT patterning are affected...

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PMID: 40610383
DOI: 10.1080/19491034.2025.2524909

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