Article
The immunologic functions of the neonatal Fc receptor for IgG.
Journal of clinical immunology - 1 Jan 2013
Rath Timo, Kuo Timothy T, Baker Kristi, Qiao Shuo-Wang, Kobayashi Kanna, Yoshida Masaru, Roopenian Derry, Fiebiger Edda, Lencer Wayne I, Blumberg Richard S
Abstract excerpt
Careful regulation of the body's immunoglobulin G (IgG) and albumin concentrations is necessitated by the importance of their respective functions. As such, the neonatal Fc receptor (FcRn), as a single receptor, is capable of regulating both of these molecules and has become an important focus of investigation. In addition to these essential protection functions, FcRn possesses a number of other functions that...
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