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Article

PCR amplification and high throughput sequencing of immunoglobulin heavy chain genes from formalin-fixed paraffin-embedded human biopsies.

Experimental and molecular pathology - 1 Feb 2013

Tabibian-Keissar Hilla, Schibby Ginette, Michaeli Miri, Rakovsky-Shapira Aviya, Azogui-Rosenthal Noemie, Dunn-Walters Deborah K, Rosenblatt Kinneret, Mehr Ramit, Barshack Iris

Abstract excerpt

The use of high throughput sequencing (HTS) technologies in biomedicine is expanding in a variety of fields in recent years. The 454 system is an HTS platform that is ideally suited to characterize B cell receptor (BCR) repertoires by sequencing of immunoglobulin (Ig) genes, as it is able to sequence stretches of several hundred nucleotides. Most studies that used this platform for antibody repertoire analyses...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22944223
DOI: 10.1016/j.yexmp.2012.08.002

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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