Article
PCR amplification and high throughput sequencing of immunoglobulin heavy chain genes from formalin-fixed paraffin-embedded human biopsies.
Experimental and molecular pathology - 1 Feb 2013
Tabibian-Keissar Hilla, Schibby Ginette, Michaeli Miri, Rakovsky-Shapira Aviya, Azogui-Rosenthal Noemie, Dunn-Walters Deborah K, Rosenblatt Kinneret, Mehr Ramit, Barshack Iris
Abstract excerpt
The use of high throughput sequencing (HTS) technologies in biomedicine is expanding in a variety of fields in recent years. The 454 system is an HTS platform that is ideally suited to characterize B cell receptor (BCR) repertoires by sequencing of immunoglobulin (Ig) genes, as it is able to sequ...
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