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Natural resistance to cancers: a Darwinian hypothesis to explain Peto’s paradox

3 Sept 2012

Abstract excerpt

BACKGROUND: Peto's paradox stipulates that there is no association between body mass (a surrogate of number of cells and longevity) and cancer prevalence in wildlife species. Resolving this paradox is a very promising research direction to understand mechanisms of cancer resistance. As of present, research has been focused on the consequences of these evolutionary pressures rather than of their causes....

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PMID: 22943484
DOI: 10.1186/1471-2407-12-387

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