Article
Absence of Yps7p, a putative glycosylphosphatidylinositol-linked aspartyl protease in Pichia pastoris, results in aberrant cell wall composition and increased osmotic stress resistance.
FEMS yeast research - 1 Dec 2012
Guan Bo, Lei Jianyong, Su Shuai, Chen Fengxiang, Duan Zuoying, Chen Yun, Gong Xiaohai, Li Huazhong, Jin Jian
Abstract excerpt
Recently, studies performed on Saccharomyces cerevisiae and Candida albicans have confirmed the importance of fungal glycosylphosphatidylinositol (GPI)-anchored aspartyl proteases (yapsins) for cell-wall integrity. Genome sequence annotation of Pichia pastoris also revealed seven putative GPI-anchored aspartyl protease genes. The five yapsin genes assigned as YPS1, YPS2, YPS3, YPS7 and MKC7 in P. pastoris were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.