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Article

A novel role for a glycosylphosphatidylinositol-anchored aspartyl protease, CgYps1, in the regulation of pH homeostasis in Candida glabrata.

Molecular microbiology - 1 Feb 2011

Bairwa Gaurav, Kaur Rupinder

Abstract excerpt

Proteases, key virulence factors of many bacterial and fungal pathogens, are pivotally important for nutrient acquisition, invasion and adherence to host cells and evasion/escape from host immune cells. In this study, we report a novel role for CgYps1, member of a family of 11 GPI-linked aspartyl proteases, in a human opportunistic fungal pathogen, Candida glabrata, in the regulation of pH homeostasis under...

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Identifiers

PMID: 21299646
DOI: 10.1111/j.1365-2958.2010.07496.x

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GPI

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