Article
Associations of Lys939Gln and Ala499Val polymorphisms of the XPC gene with cancer susceptibility: a meta-analysis.
International journal of cancer - 15 Oct 2013
He Jing, Shi Ting-Yan, Zhu Mei-Ling, Wang Meng-Yun, Li Qiao-Xin, Wei Qing-Yi
Abstract excerpt
XPC polymorphisms may alter DNA repair capacity, thus leading to genetic instability and carcinogenesis. Numerous studies have investigated the associations of XPC Lys939Gln (rs2228001) and Ala499Val (rs2228000) polymorphisms with cancer susceptibility; however, the findings are inconclusive. We searched literature from MEDLINE and EMBASE for eligible publications that assessed the associations between these two...
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