Article
Mitochondrial DNA and TFAM gene variation in early-onset myocardial infarction: evidence for an association to haplogroup H.
Mitochondrion - 1 Jan 2011
Palacín María, Alvarez Victoria, Martín María, Díaz Marta, Corao Ana I, Alonso Belén, Díaz-Molina Beatriz, Lozano Iñigo, Avanzas Pablo, Morís César, Reguero Julián R, Rodríguez Isabel, López-Larrea Carlos, Cannata-Andía Jorge, Batalla Alberto, Ruiz-Ortega Marta, Martínez-Camblor Pablo, Coto Eliecer
Abstract excerpt
The main objective of this research was to define the association between common mitochondrial DNA (mtDNA) polymorphisms and mitochondrial transcription A gene (TFAM) variants and myocardial infarction (MI) in patients with atherosclerotic diseased vessels. Ten mitochondrial polymorphisms that defined the nine common European haplogroups were genotyped in 500 male patients with early onset MI (<55 years) and at...
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