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Article

A potential role for insulin resistance in experimental pulmonary hypertension.

The European respiratory journal - 1 Apr 2013

West James, Niswender Kevin D, Johnson Jennifer A, Pugh Meredith E, Gleaves Linda, Fessel Joshua P, Hemnes Anna R

Abstract excerpt

Patients with pulmonary arterial hypertension have increased prevalence of insulin resistance. We aimed to determine whether metabolic defects are associated with bone morphogenic protein receptor type 2 (Bmpr2) mutations in mice, and whether these may contribute to pulmonary vascular disease development. Metabolic phenotyping was performed on transgenic mice with inducible expression of Bmpr2 mutation, R899X....

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Identifiers

PMID: 22936709
DOI: 10.1183/09031936.00030312
PMCID: PMC3746982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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