Article
Insulin-like growth factor II and its receptors in atherosclerosis and in conditions predisposing to atherosclerosis.
Current opinion in lipidology - 1 Oct 2003
Zaina Silvio, Nilsson Jan
Abstract excerpt
PURPOSE OF REVIEW: Growth factors regulate cellular migration, proliferation, and the production of extracellular matrix during the development of the atherosclerotic lesion. Here we discuss experimental evidence pointing to insulin-like growth factor II and its receptors as important players in cardiovascular diseases. RECENT FINDINGS: Genetically modified mice with altered levels of insulin-like growth factor...
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