Article
The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study.
PLoS medicine - 1 Oct 2011
Do Ron, Xie Changchun, Zhang Xiaohe, Männistö Satu, Harald Kennet, Islam Shofiqul, Bailey Swneke D, Rangarajan Sumathy, McQueen Matthew J, Diaz Rafael, Lisheng Liu, Wang Xingyu, Silander Kaisa, Peltonen Leena, Yusuf Salim, Salomaa Veikko, Engert James C, Anand Sonia S
Abstract excerpt
BACKGROUND: One of the most robust genetic associations for cardiovascular disease (CVD) is the Chromosome 9p21 region. However, the interaction of this locus with environmental factors has not been extensively explored. We investigated the association of 9p21 with myocardial infarction (MI) in individuals of different ethnicities, and tested for an interaction with environmental factors. METHODS AND FINDINGS: We...
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