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Article

The fate of bone marrow-derived cells carrying a Polycystic Kidney Disease mutation in the genetically normal kidney.

BMC nephrology - 29 Aug 2012

Verghese Elizabeth, Johnson Chad, Bertram John F, Ricardo Sharon D, Deane James A

Abstract excerpt

BACKGROUND: Polycystic Kidney Disease (PKD) is a genetic condition in which dedifferentiated and highly proliferative epithelial cells form renal cysts and is frequently treated by renal transplantation. Studies have reported that bone marrow-derived cells give rise to renal epithelial cells, particularly following renal injury as often occurs during transplantation. This raises the possibility that bone...

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Identifiers

PMID: 22931547
DOI: 10.1186/1471-2369-13-91
PMCID: PMC3502565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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