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Article

Autophagy and apoptosis-related genes in chronic liver disease and hepatocellular carcinoma

28 Aug 2012

Abstract excerpt

BACKGROUND: Dysregulation of autophagy is important in the pathogenesis of many diseases, including cancer. Several aspects of the biological role of autophagy are however still unclear and the relationship between apoptosis and autophagy, particularly in the liver has yet to be thoroughly explored. In this study we evaluated the expression of Beclin 1 (one of the main autophagocytic agents, which bridges...

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PMID: 22928777
DOI: 10.1186/1471-230x-12-118

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