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Article

Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury.

Hepatology (Baltimore, Md.) - 1 May 2004

Walsh Meagan J, Vanags Daina M, Clouston Andrew D, Richardson Michelle M, Purdie David M, Jonsson Julie R, Powell Elizabeth E

Abstract excerpt

Steatosis is increasingly recognized as a cofactor influencing the progression of fibrosis in chronic hepatitis C; however, the mechanisms by which it contributes to liver injury remain uncertain. We studied 125 patients with chronic hepatitis C to assess the effect of steatosis on liver cell apoptosis and the expression of Bcl-2, Bcl-x(L), Bax, and tumor necrosis factor alpha (TNF-alpha) and the relationship...

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PMID: 15122751
DOI: 10.1002/hep.20179

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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