Article
Expression of pro- and anti-inflammatory cytokines in relation to apoptotic genes in Egyptian liver disease patients associated with HCV-genotype-4.
Journal of gastroenterology and hepatology - 1 Mar 2009
Zekri Abdel-Rahman N, Bahnassy Abeer A, Abdel-Wahab Sabrin A, Khafagy Medhat M, Loutfy Samah A, Radwan Hessam, Shaarawy Sabry M
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common tumors worldwide strongly linked to hepatitis C virus (HCV) infection. However, the exact pathogenetic mechanisms are still unclear. METHODS: We assessed the expression of apoptosis genes (GSK3-B, AKT-1, Bcl-2), inflammatory cytokines (TNFalpha, TNF-RI, TNF-RII, IL-6, IL-6R), anti-inflammatory IL-10, CRP and alphaFP by reverse...
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