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Article

Low expression of Beclin 1, associated with high Bcl-xL, predicts a malignant phenotype and poor prognosis of gastric cancer.

Autophagy - 1 Mar 2012

Zhou Wei-Hua, Tang Fang, Xu Jie, Wu Xing, Yang Shao-Bing, Feng Zhi-Ying, Ding Yun-Gang, Wan Xiang-Bo, Guan Zhong, Li Hai-Gang, Lin Dong-Jun, Shao Chun-Kui, Liu Quentin

Abstract excerpt

Recent studies have suggested that dysregulation of autophagy plays a pivotal role in tumorigenesis. Here, we determined the prognostic value of autophagy-related protein Beclin 1 in gastric cancer. A total of 153 primary gastric cancer patients were subjected to analysis of Beclin 1 expression and survival prognosis. Among them, 68 patients were assigned randomly and used as a training set to generate a cutoff...

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Identifiers

PMID: 22240664
DOI: 10.4161/auto.18641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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