Article
Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma.
Autophagy - 1 Apr 2009
Shi Ying-Hong, Ding Zhen-Bin, Zhou Jian, Qiu Shuang-Jian, Fan Jia
Abstract excerpt
Autophagy is believed to be important in tumorigenesis and tumor progression. However, the role of autophagy in hepatocellular carcinoma (HCC), and especially the prognostic value of autophagic proteins, has not been investigated. Our studies described here show decreased basal expression of autophagic genes and their corresponding autophagic activity under conditions of starvation in HCC cell lines, and the...
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