Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The relation of vascular endothelial growth factor (VEGF) gene polymorphisms on VEGF levels and the risk of vasoocclusive crisis in sickle cell disease.

European journal of haematology - 1 Nov 2012

Al-Habboubi Hebah H, Mahdi Najat, Abu-Hijleh Tala M, Abu-Hijleh Farah M, Sater Mai S, Almawi Wassim Y

Abstract excerpt

OBJECTIVE: The association of vascular endothelial growth factor (VEGFA) variants and VEGF secretion with sickle cell disease (SCD) vasoocclusive crisis (VOC) was investigated in 210 VOC patients and 114 pain-free control patients. METHODS: VEGFA -2578C/A (rs699947), -460T/C (rs833061), -1154G/A (rs15703060), -634G/C (rs2010963), 398G/A (rs833068), 497G/A (), -583T/C (), and 936C/T ()...

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell
Share to Child, Preschool
Share to Heterozygote
Share to Homozygote
Share to Linkage Disequilibrium
Share to Vascular Diseases
Share to Vascular Endothelial Growth Factor A
Share to Young Adult

Source

Identifiers

PMID: 22925497
DOI: 10.1111/ejh.12003

Genes

VEGFA
SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The relation of vascular endothelial growth factor (VEGF) gene polymorphisms on VEGF levels and the risk of vasoocclusive crisis in sickle cell disease.PMID 22925497Read ↗

Impact of VEGFA -583C > T polymorphism on serum VEGF levels and the susceptibility to acute chest syndrome in pediatric patients with sickle cell disease.Semantic proximity Read ↗

Contribution of VEGF polymorphisms to variation in VEGF serum levels in a healthy population.Semantic proximity Read ↗

Protein Z polymorphisms associated with vaso-occlusive crisis in young sickle cell disease patients.Semantic proximity Read ↗

Human platelet alloantigens (HPA) 1, HPA2, HPA3, HPA4, and HPA5 polymorphisms in sickle cell anemia patients with vaso-occlusive crisis.Semantic proximity Read ↗

A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene polymorphisms and the risk of vasculopathy in sickle cell disease.Semantic proximity Read ↗

Association of KLOTHO polymorphisms with clinical complications of sickle cell anemia.Semantic proximity Read ↗

Association of the MBL2 gene EXON1 polymorphism and vasoocclusive crisis in patients with sickle cell anemia.Semantic proximity Read ↗

Plasma inflammatory and angiogenic protein profiling of patients with sickle cell diseaseSemantic proximity Read ↗

Incidence and risk factors of pain crisis after hematopoietic cell transplantation for sickle cell diseaseSemantic proximity Read ↗

Association of variant alleles of MBL2 gene with vasoocclusive crisis in children with sickle cell anemia.Semantic proximity Read ↗

Clinical correlates of acute pulmonary events in children and adolescents with sickle cell disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.