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Article

Human platelet alloantigens (HPA) 1, HPA2, HPA3, HPA4, and HPA5 polymorphisms in sickle cell anemia patients with vaso-occlusive crisis.

European journal of haematology - 1 Dec 2009

Al-Subaie Abeer M, Fawaz Naglaa A, Mahdi Najat, Al-Absi Iman K, Al-Ola Khadija, Ameen Ghada, Almawi Wassim Y

Abstract excerpt

OBJECTIVES: Vaso-occlusive crisis (VOC) is a significant cause of morbidity and mortality in sickle cell anemia (SCA) patients. Insofar as polymorphism in human platelet alloantigen (HPA) exhibit a prothrombotic nature, we hypothesized that specific HPA polymorphic variants are associated with VOC. We investigated the distribution of HPA1, HPA2, HPA3, HPA4, and HPA5 alleles genotypes among VOC and non-VOC control...

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Identifiers

PMID: 19702628
DOI: 10.1111/j.1600-0609.2009.01339.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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