Article
In vitro molecular characterization of RNA-proteins interactions during initiation of translation of a wild-type and a mutant Coxsackievirus B3 RNAs.
Molecular biotechnology - 1 Jun 2013
Souii Amira, M'hadheb-Gharbi Manel Ben, Aouni Mahjoub, Gharbi Jawhar
Abstract excerpt
Translation initiation of Coxsackievirus B3 (CVB3) RNA is directed by an internal ribosome entry site (IRES) within the 5' untranslated region. Host cell factors involved in this process include some canonical translation factors and additional RNA-binding proteins. We have, previously, described that the Sabin3-like mutation (U475 → C) introduced in CVB3 genome led to a defective mutant with a serious reduction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
