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Article

[Selected mice models based on APP, MAPT and presenilin gene mutations in research on the pathogenesis of Alzheimer's disease].

Postepy higieny i medycyny doswiadczalnej (Online) - 22 Jun 2012

Więdłocha Magdalena, Stańczykiewicz Bartłomiej, Jakubik Marta, Rymaszewska Joanna

Abstract excerpt

The research conducted on animal models of Alzheimer's disease (AD) has provided valuable information about the pathogenesis of this disease and associated behavioral and cognitive deficits as well as the disease-associated anatomical and histopathological lesions of the brain. Transgenic technologies have enabled the creation of animal models based on mutations in APP, MAPT, presenilin genes, tau protein and...

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Source

Identifiers

PMID: 22922141
DOI: 10.5604/17322693.1001098

Genes

APP
MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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