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Article

[Functional analysis of SNPs in porcine TLR4 gene].

Yi chuan = Hereditas - 1 Aug 2012

Yang Xiu-Qin, Chen Yue-Chan, Wang Liang, Li Hai-Tao, Liu Di, Guan Qing-Zhi, Fu Bo

Abstract excerpt

Toll-like receptor 4 (TLR4) plays an important role in immune response and the polymorphism in it might affect protein signaling and host resistance/susceptibility to disease. This study was designed to characterize the functional relevance of 3 nonsynonymous single nucleotide polymorphisms (SNPs), c.611 T>A (p.Leu204His), c.1027 C>A (p.Gln343Lys), and c.1605 G>T (p.Leu535Phe), which were selected based on our...

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Source

Identifiers

PMID: 22917910
DOI: 10.3724/sp.j.1005.2012.01050

Genes

TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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