Article
Expression of laminin-5 and integrins in actinic cheilitis and superficially invasive squamous cell carcinomas of the lip.
Pathology, research and practice - 15 Oct 2012
Peixoto da-Silva Janaína, Lourenço Silvia, Nico Marcello, Silva Filomena H, Martins Marília Trierveiler, Costa-Neves Adriana
Abstract excerpt
The progression of carcinogenesis entails the detachment of cells, invasion and migration of neoplastic cells. Alterations in epithelial adhesion and basement membrane proteins might mediate the early stages of carcinogenesis. This study investigated the expression of adhesion molecules and the basement membrane protein laminin-5 in actinic cheilitis (AC) and incipient squamous cell carcinoma of the lower lip to...
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