Article
Actinic cheilitis: histopathology and p53.
Journal of cutaneous pathology - 1 Aug 2006
Neto Pimentel Dalva Regina, Michalany Nilceo, Alchorne Mauricio, Abreu Marilda, Borra Ricardo Carneiro, Weckx Luc
Abstract excerpt
BACKGROUND: Chronic actinic cheilitis (AC) is a precursor of squamous cell carcinoma (SCC) of the lip. OBJECTIVES: To evaluate the histopathological characteristics that may help to identify AC more susceptible to carcinomatous transformation, to assess the p53 protein expression in AC, and to determine the value of the p53 expression as a marker of transformation into SCC of the lip. METHODS: Seventy cases of...
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