Article
Mutation screening of the HTR2B gene in patients with Tourette syndrome.
Neuroscience letters - 27 Sept 2012
Guo Yi, Deng Xiong, Jankovic Joseph, Su Linyan, Zhang Jie, Le Weidong, Xu Hongbo, Yang Zuocheng, Tang Jinsong, Kuang Shoujin, Deng Hao
Abstract excerpt
Tourette syndrome (TS), a neurological disorder with a reported prevalence frequency ranging from 0.7% to 4.2%, is manifested by motor and phonic tics and associated with a variety of behavioral abnormalities including impulsivity. Clinical, neuroimaging and other studies support dysfunction of the dopamine and 5-hydroxytryptamine neurotransmitter systems in TS. To determine whether TS is associated with mutation...
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