Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tourette syndrome and the norepinephrine transporter gene: results of a systematic mutation screening.

American journal of medical genetics - 16 Apr 1999

Stöber G, Hebebrand J, Cichon S, Brüss M, Bönisch H, Lehmkuhl G, Poustka F, Schmidt M, Remschmidt H, Propping P, Nöthen M M

Abstract excerpt

Tourette syndrome (TS) is a complex inherited neuropsychiatric disorder characterized by multiple motor and phonic tics. Involvement of central norepinephrine mechanisms is suggested by central norepinephrinic hyperactivity in patients with TS and by the therapeutic effects of the presynaptic alpha2-adrenergic agonist clonidine. The norepinephrine transporter gene (NET) was systematically screened by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Norepinephrine Plasma Membrane Transport Proteins

Share to Point Mutation

Share to Polymorphism, Restriction Fragment Length

Share to Symporters

Share to Tourette Syndrome

Source

Identifiers

PMID: 10206236
DOI: 10.1002/(sici)1096-8628(19990416)88:2<158::aid-ajmg12>3.0.co;2-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tourette syndrome and the norepinephrine transporter gene: results of a systematic mutation screening.PMID 10206236Read ↗

Norepinephrine transporter polymorphisms in Tourette syndrome with and without attention deficit hyperactivity disorder: no evidence for significant association.Semantic proximity Read ↗

Systematic search for variation in the human norepinephrine transporter gene: identification of five naturally occurring missense mutations and study of association with major psychiatric disorders.Semantic proximity Read ↗

Genetics of Tourette Syndrome.Semantic proximity Read ↗

Genetic or acquired deficits in the norepinephrine transporter: current understanding of clinical implicationsSemantic proximity Read ↗

Dopaminergic polymorphisms in Tourette syndrome: association with the DAT gene (SLC6A3).Semantic proximity Read ↗

Mutation screening of the HTR2B gene in patients with Tourette syndrome.Semantic proximity Read ↗

Functional gene variation in the human norepinephrine transporter: association with attention deficit hyperactivity disorder.Semantic proximity Read ↗

A genetic variant of HTR2C may play a role in the manifestation of Tourette syndrome.Semantic proximity Read ↗

Gilles de la Tourette syndrome: the complexities of phenotype and treatment.Semantic proximity Read ↗

Dopaminergic candidate genes in Tourette syndrome: association between tic severity and 3' UTR polymorphism of the dopamine transporter gene.Semantic proximity Read ↗

Lack of association between SLC5A7 polymorphisms and Tourette syndrome in a Chinese Han population.Semantic proximity Read ↗

The Gilles de la Tourette syndrome: the current status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.