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Article

A genetic polymorphism of FREM1 is associated with resistance against HIV infection in the Pumwani sex worker cohort.

Journal of virology - 1 Nov 2012

Luo Ma, Sainsbury James, Tuff Jeffrey, Lacap Philip A, Yuan Xin-Yong, Hirbod Taha, Kimani Joshua, Wachihi Charles, Ramdahin Sue, Bielawny Thomas, Embree Joanne, Broliden Kristina, Ball T Blake, Plummer Francis A

Abstract excerpt

A subgroup of women enrolled in the Pumwani sex worker cohort remain seronegative and PCR negative for human immunodeficiency virus type 1 despite repeated exposure through high-risk sex work. Studies have shown that polymorphisms of genes involved in antigen presentation and viral restriction factors are associated with resistance to HIV infection. To discover other possible genetic factors underlying this...

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Source

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Identifiers

PMID: 22915813
DOI: 10.1128/JVI.01499-12
PMCID: PMC3486297

Genes

FREM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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