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Article

The Potential Role of FREM1 and Its Isoform TILRR in HIV-1 Acquisition through Mediating Inflammation.

International journal of molecular sciences - 22 Jul 2021

Kashem Mohammad Abul, Li Hongzhao, Liu Lewis Ruxi, Liang Binhua, Omange Robert Were, Plummer Francis A, Luo Ma

Abstract excerpt

FREM1 (Fras-related extracellular matrix 1) and its splice variant TILRR (Toll-like interleukin-1 receptor regulator) have been identified as integral components of innate immune systems. The potential involvement of FREM1 in HIV-1 (human immunodeficiency virus 1) acquisition was suggested by a genome-wide SNP (single nucleotide polymorphism) analysis of HIV-1 resistant and susceptible sex workers enrolled in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 34360591
DOI: 10.3390/ijms22157825
PMCID: PMC8346017

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