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Article

A novel hierarchical prognostic model of AML solely based on molecular mutations.

Blood - 11 Oct 2012

Grossmann Vera, Schnittger Susanne, Kohlmann Alexander, Eder Christiane, Roller Andreas, Dicker Frank, Schmid Christoph, Wendtner Clemens-Martin, Staib Peter, Serve Hubert, Kreuzer Karl-Anton, Kern Wolfgang, Haferlach Torsten, Haferlach Claudia

Abstract excerpt

The karyotype is so far the most important prognostic parameter in acute myeloid leukemia (AML). Molecular mutations have been analyzed to subdivide AML with normal karyotype into prognostic subsets. The aim of this study was to develop a prognostic model for the entire AML cohort solely based on molecular markers. One thousand patients with cytogenetic data were investigated for the following molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 22915647
DOI: 10.1182/blood-2012-03-419622

Genes

RUNX1
ASXL1
CBFB
FLT3
MYH11
NPM1
PML
RARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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