Article
HLA and SNP haplotype mapping in the Japanese population.
Genes and immunity - 1 Oct 2012
Kitajima H, Sonoda M, Yamamoto K
Abstract excerpt
The genes that encode the human leukocyte antigen (HLA) class I and II molecules are highly polymorphic and located in the major histocompatibility complex (MHC) region, where there is a high density of immune-related genes. Numerous studies have identified disease susceptibility in this region; however, interpretation of the results is complicated because of the strong linkage disequilibrium (LD) among HLA...
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