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Article

Pla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterol.

PloS one - 1 Jan 2012

Aljakna Aleksandra, Choi Seungbum, Savage Holly, Hageman Blair Rachael, Gu Tongjun, Svenson Karen L, Churchill Gary A, Hibbs Matt, Korstanje Ron

Abstract excerpt

Despite considerable progress understanding genes that affect the HDL particle, its function, and cholesterol content, genes identified to date explain only a small percentage of the genetic variation. We used N-ethyl-N-nitrosourea mutagenesis in mice to discover novel genes that affect HDL chole...

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Identifiers

PMID: 22912808
DOI: 10.1371/journal.pone.0043139
PMCID: PMC3422231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22912808-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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