Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myostatin facilitates slow and inhibits fast myosin heavy chain expression during myogenic differentiation.

Biochemical and biophysical research communications - 14 Sept 2012

Wang Min, Yu Hui, Kim Yong Soo, Bidwell Christopher A, Kuang Shihuan

Abstract excerpt

Skeletal muscles in the limb and body trunk are composed of heterogeneous myofibers expressing different isoforms of myosin heavy chain (Myh), including type I (slow, Myh7), IIA (intermediate, Myh2), IIX (fast, Myh1), and IIB (very fast, Myh4). While the contraction force and speed of a muscle are known to be determined by the relative abundance of myofibers expressing each Myh isoform, it is unclear how specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Knockout Techniques
Share to Muscle Development

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscle Fibers, Fast-Twitch

Share to Muscle Fibers, Slow-Twitch

Share to Muscle, Skeletal

Share to Myoblasts, Skeletal

Share to Myosin Heavy Chains

Share to Myostatin

Source

Open in PubMed Open full text

Identifiers

PMID: 22910409
DOI: 10.1016/j.bbrc.2012.08.040
PMCID: PMC3483024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myostatin facilitates slow and inhibits fast myosin heavy chain expression during myogenic differentiation.PMID 22910409Read ↗

The mammalian myosin heavy chain gene family.Semantic proximity Read ↗

Myostatin's marvels: From muscle regulator to diverse implications in health and diseaseSemantic proximity Read ↗

The compact mutation of myostatin causes a glycolytic shift in the phenotype of fast skeletal muscles.Semantic proximity Read ↗

INVITED REVIEW: Inhibitors of myostatin as methods of enhancing muscle growth and development.Semantic proximity Read ↗

The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis.Semantic proximity Read ↗

Myostatin Regulates Cardiomyocyte Growth Through Modulation of Akt SignalingSemantic proximity Read ↗

Myostatin, a negative regulator of muscle mass: implications for muscle degenerative diseasesSemantic proximity Read ↗

Therapeutic applications and challenges in myostatin inhibition for enhanced skeletal muscle mass and functionsSemantic proximity Read ↗

Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects.Semantic proximity Read ↗

Myostatin Inhibitors: Panacea or Predicament for Musculoskeletal Disorders?Semantic proximity Read ↗

Myostatin: a modulator of skeletal-muscle stem cellsSemantic proximity Read ↗

Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.