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Current Translational Research and Murine Models For Duchenne Muscular Dystrophy

3 Mar 2016

Abstract excerpt

Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder characterized by progressive muscle degeneration. Mutations in the DMD gene result in the absence of dystrophin, a protein required for muscle strength and stability. Currently, there is no cure for DMD. Since murine models are relatively easy to genetically manipulate, cost effective, and easily reproducible due to their short generation time,...

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PMID: 27854202
DOI: 10.3233/jnd-150113

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