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The ESR2 AluI 1730G>A (rs4986938) gene polymorphism is associated with fibrinogen plasma levels in postmenopausal women.

Gene - 25 Oct 2012

Marini Herbert, Currò Monica, Adamo Elena B, Polito Francesca, Ferlazzo Nadia, Bitto Alessandra, Atteritano Marco, D'Anna Rosario, Alibrandi Angela, Altavilla Domenica, Squadrito Francesco, Ientile Riccardo, Caccamo Daniela

Abstract excerpt

The incidence of cardiovascular disease (CVD) and resultant morbidity and mortality are highly increased in postmenopausal women. Recent observations indicate the involvement of estrogen receptor beta in the pathogenesis of CVD, and the potential role of ESR2 gene polymorphisms as independent risk factors for CVD. We aimed to investigate the possible association between the ESR2 AluI 1730G>A gene polymorphism...

Topics

Alu Elements
Body Mass Index
Cardiovascular Diseases
Estrogen Receptor beta
Female
Fibrinogen
Genetic Predisposition to Disease
Humans
Middle Aged
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Postmenopause

Prognosis

Risk Factors

Source

Identifiers

PMID: 22906475
DOI: 10.1016/j.gene.2012.08.004

Genes

ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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