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Mitochondrial OXA Translocase Plays a Major Role in Biogenesis of Inner-Membrane Proteins.

Cell metabolism - 10 May 2016

Stiller Sebastian B, Höpker Jan, Oeljeklaus Silke, Schütze Conny, Schrempp Sandra G, Vent-Schmidt Jens, Horvath Susanne E, Frazier Ann E, Gebert Natalia, van der Laan Martin, Bohnert Maria, Warscheid Bettina, Pfanner Nikolaus, Wiedemann Nils

Abstract excerpt

The mitochondrial inner membrane harbors three protein translocases. Presequence translocase and carrier translocase are essential for importing nuclear-encoded proteins. The oxidase assembly (OXA) translocase is required for exporting mitochondrial-encoded proteins; however, different views exist about its relevance for nuclear-encoded proteins. We report that OXA plays a dual role in the biogenesis of...

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Identifiers

PMID: 27166948
DOI: 10.1016/j.cmet.2016.04.005
PMCID: PMC4873616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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