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Article

Oxytocin-stimulated NFAT transcriptional activation in human myometrial cells.

Molecular endocrinology (Baltimore, Md.) - 1 Oct 2012

Pont Jason N A, McArdle Craig A, López Bernal Andrés

Abstract excerpt

Oxytocin (OXT) is a peptide hormone that binds the OXT receptor on myometrial cells, initiating an intracellular signaling cascade, resulting in accumulation of intracellular calcium and smooth muscle contraction. In other systems, an elevation of intracellular Ca(2+) stimulates nuclear translocation of the transcription factor, nuclear factor of activated T cells (NFAT), which is transcriptionally active in...

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Source

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Identifiers

PMID: 22902539
DOI: 10.1210/me.2012-1057
PMCID: PMC3507519

Genes

OXT
NFATC1
RCAN1
RGS2
PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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