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Article

Nuclear factor of activated T-cells transcription factors in the vasculature: the good guys or the bad guys?

3 Sept 2008

Abstract excerpt

PURPOSE OF REVIEW: The nuclear factor of activated T-cells (NFAT) proteins are a family of Ca/calcineurin-dependent transcription factors that were first characterized in T-lymphocytes as inducers of cytokine gene expression. Since then, NFAT proteins have been shown to play varied roles outside of the immune system, including in the cardiovascular system. Cells in the vessel wall display a diverse array of Ca...

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PMID: 18769229
DOI: 10.1097/mol.0b013e32830dd545

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