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Article

AIP limits neurotransmitter release by inhibiting calcium bursts from the ryanodine receptor.

Nature communications - 9 Nov 2017

Chen Bojun, Liu Ping, Hujber Edward J, Li Yan, Jorgensen Erik M, Wang Zhao-Wen

Abstract excerpt

Pituitary tumors are frequently associated with mutations in the AIP gene and are sometimes associated with hypersecretion of growth hormone. It is unclear whether other factors besides an enlarged pituitary contribute to the hypersecretion. In a genetic screen for suppressors of reduced neurotransmitter release, we identified a mutation in Caenorhabditis elegans AIPR-1 (AIP-related-1), which causes profound...

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Source

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Identifiers

PMID: 29123133
DOI: 10.1038/s41467-017-01704-z
PMCID: PMC5680226

Genes

AIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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