Caenorhabditis elegans wsp-1 regulation of synaptic function at the neuromuscular junction.

doi:10.1074/jbc.M109.096164

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Article

Caenorhabditis elegans wsp-1 regulation of synaptic function at the neuromuscular junction.

The Journal of biological chemistry - 23 Jul 2010

Zhang Yuqian, Kubiseski Terrance J

Abstract excerpt

The Rho GTPase members and their effector proteins, such as the Wiskott-Aldrich syndrome protein (WASP), play critical roles in regulating actin dynamics that affect cell motility, endocytosis, cell division, and transport. It is well established that Caenorhabditis elegans wsp-1 plays an essential role in embryonic development. We were interested in the role of the C. elegans protein WSP-1 in the adult nematode....

Topics

Actins
Aldicarb
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cytoskeleton
DNA Mutational Analysis
Kinetics
Mutation
Neuromuscular Junction
Neurons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Organ Specificity

Paralysis

Phenotype

Protein Structure, Tertiary

Synaptic Transmission

cdc42 GTP-Binding Protein

Source

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Identifiers

PMID: 20501656
DOI: 10.1074/jbc.M109.096164
PMCID: PMC2906297

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