Article
The large-scale distribution of somatic mutations in cancer genomes.
Human mutation - 1 Jan 2012
Hodgkinson Alan, Chen Ying, Eyre-Walker Adam
Abstract excerpt
Recently, the genome sequences from several cancers have been published, along with the genome from a noncancer tissue from the same individual, allowing the identification of new somatic mutations in the cancer. We show that there is significant variation in the density of mutations at the 1-Mb scale within three cancer genomes and that the density of mutations is correlated between them. We also demonstrate...
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