FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the POUNDS LOST Trial.

doi:10.2337/db11-1799

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the POUNDS LOST Trial.

Diabetes - 1 Nov 2012

Zhang Xiaomin, Qi Qibin, Zhang Cuilin, Smith Steven R, Hu Frank B, Sacks Frank M, Bray George A, Qi Lu

Abstract excerpt

Recent evidence suggests that the fat mass and obesity-associated gene (FTO) genotype may interact with dietary intakes in relation to adiposity. We tested the effect of FTO variant on weight loss in response to 2-year diet interventions. FTO rs1558902 was genotyped in 742 obese adults who were randomly assigned to one of four diets differing in the proportions of fat, protein, and carbohydrate. Body composition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Fat Distribution

Share to Boston

Share to Diet, Reducing

Share to Dietary Proteins

Share to Louisiana

Share to Overweight

Share to Weight Loss

Source

Open in PubMed Open full text

Identifiers

PMID: 22891219
DOI: 10.2337/db11-1799
PMCID: PMC3478519

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the POUNDS LOST Trial.PMID 22891219Read ↗

Dietary Fat Modifies the Effects of FTO Genotype on Changes in Insulin Sensitivity.Semantic proximity Read ↗

APOA5 genotype modulates 2-y changes in lipid profile in response to weight-loss diet intervention: the Pounds Lost Trial.Semantic proximity Read ↗

FTO genotype and weight loss in diet and lifestyle interventions: a systematic review and meta-analysis.Semantic proximity Read ↗

FTO genotype, dietary protein, and change in appetite: the Preventing Overweight Using Novel Dietary Strategies trial.Semantic proximity Read ↗

FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials.Semantic proximity Read ↗

The rs9939609 gene variant in FTO modified the metabolic response of weight loss after a 3-month intervention with a hypocaloric diet.Semantic proximity Read ↗

TFAP2B -dietary protein and glycemic index interactions and weight maintenance after weight loss in the DiOGenes trial.Semantic proximity Read ↗

Toward Precision Weight-Loss Dietary Interventions: Findings from the POUNDS Lost TrialSemantic proximity Read ↗

Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.Semantic proximity Read ↗

TFAP2B influences the effect of dietary fat on weight loss under energy restriction.Semantic proximity Read ↗

TCF7L2 genetic variants modulate the effect of dietary fat intake on changes in body composition during a weight-loss intervention.Semantic proximity Read ↗

CETP genotype and changes in lipid levels in response to weight-loss diet intervention in the POUNDS LOST and DIRECT randomized trials.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.