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Article

FTO genotype and weight loss in diet and lifestyle interventions: a systematic review and meta-analysis.

The American journal of clinical nutrition - 1 Apr 2016

Xiang Lingwei, Wu Hongyu, Pan An, Patel Bhakti, Xiang Guangda, Qi Lu, Kaplan Robert C, Hu Frank, Wylie-Rosett Judith, Qi Qibin

Abstract excerpt

BACKGROUND: Studies have suggested that the fat mass and obesity-associated (FTO) genotype is associated with individual variability in weight loss in response to diet/lifestyle interventions, but results are inconsistent. OBJECTIVE: We aimed to provide a summary of the literature evaluating the relation between the FTO genotype and weight loss in response to diet/lifestyle interventions. DESIGN: A search of...

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Topics

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Weight

Share to Databases, Factual

Share to Diet, Reducing

Share to Life Style

Share to Randomized Controlled Trials as Topic

Share to Weight Loss

Source

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Identifiers

PMID: 26888713
DOI: 10.3945/ajcn.115.123448
PMCID: PMC4807705

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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FTO genotype and weight loss in diet and lifestyle interventions: a systematic review and meta-analysis.PMID 26888713Read ↗

FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials.Semantic proximity Read ↗

The sex-specific influence of FTO genotype on exercise intervention for weight loss in adult with obesity.Semantic proximity Read ↗

The rs9939609 gene variant in FTO modified the metabolic response of weight loss after a 3-month intervention with a hypocaloric diet.Semantic proximity Read ↗

The FTO genotype as a useful predictor of body weight maintenance: initial data from a 5-year follow-up study.Semantic proximity Read ↗

Effects of FTO genotype on weight loss and metabolic risk factors in response to calorie restriction among Japanese women.Semantic proximity Read ↗

FTO genotype and body mass index reduction in childhood obesity interventions: A systematic review and meta-analysis.Semantic proximity Read ↗

The A-allele of the common FTO gene variant rs9939609 complicates weight maintenance in severe obese patients.Semantic proximity Read ↗

The role of macronutrient intake in reducing the risk of obesity and overweight among carriers of different polymorphisms of FTO gene. A reviewSemantic proximity Read ↗

FTO Obesity Variant-Exercise Interaction on Changes in Body Weight and BMI: The Taiwan Biobank Study.Semantic proximity Read ↗

FTO Genotype Interacts with Improvement in Aerobic Fitness on Body Weight Loss During Lifestyle Intervention.Semantic proximity Read ↗

A 3-year intervention with a Mediterranean diet modified the association between the rs9939609 gene variant in FTO and body weight changes.Semantic proximity Read ↗

FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.Semantic proximity Read ↗

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